HORMONESMeta-Analysis
Insulin Resistance & Androgen Elevation
Hyperinsulinemia directly upregulates ovarian androgen production via theca cell stimulation — independent of body weight.
PMID 31296325Read breakdown →
// Evidence Hierarchy
Not all studies are created equal.
We prioritize the top tiers. Here is how the hierarchy of scientific evidence works.
1.We cite this
Systematic Reviews
Comprehensive analysis of all available studies on a question, with strict inclusion criteria and bias assessment.
2.We cite this
Meta-Analyses
Statistical pooling of multiple RCTs to compute a weighted average effect across thousands of participants.
3.We cite this
Randomized Controlled Trials
Gold standard experiments — participants randomly assigned to treatment or control, isolating cause and effect.
Our evidence threshold
4.
Cohort Studies
Observational research tracking groups over time. Useful for trends, but cannot prove causation alone.
5.
Case Studies
Individual patient reports. Valuable for rare conditions and hypothesis generation, not for drawing conclusions.
// Study Breakdowns
The science we stand on.
Each breakdown takes a peer-reviewed paper and explains the finding, the mechanism, and why it matters for your health.
// Weekly Research
Get a study breakdown every week.
One peer-reviewed paper, explained clearly. No fluff, no agenda — just the biology that matters for how you feel, sleep, and function.
Subscribe to the newsletterFree. Unsubscribe anytime. No spam. Ever.